Sodium PCA 50% Solution — Lightweight Humectant for Skin and Hair

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Develop hydrating skin-care and hair-care formulas with Sodium PCA, a water-soluble humectant associated with the skin's natural moisturizing factor. The working commercial grade is a colorless to pale yellow clear liquid containing approximately 50% Sodium PCA in water, offering easy weighing and water-phase incorporation without powder-dissolution steps.

Product Specifications

At a glance	Details
INCI	Sodium PCA
CAS	28874-51-3 for Sodium 5-oxo-L-prolinate; water 7732-18-5
Formula / molecular weight	C5H6NNaO3 / approximately 151.10 for Sodium PCA
Appearance	Colorless to pale yellow clear liquid
Active concentration	approximately 50% in water
Solubility	Water-soluble; not oil-soluble
Typical first screen	1-5%, equivalent to about 0.5-2.5% active at 50% concentration

Why Formulators Choose Sodium PCA

NMF-related humectancy: PCA is a major component measured in the stratum corneum's natural moisturizing factor [R6].
Lightweight hydration support: useful in formulas designed for soft, supple and comfortably hydrated-feeling skin.
Simple liquid handling: a 50% aqueous solution can be weighed directly into the water phase or suitable cool-down phase.
Skin and hair versatility: fits toners, serums, lotions, cleansers, shampoos, conditioners and scalp-care concepts.

Best-Fit Applications

Toners and essences: Adds humectancy in a light, water-based format.
Serums and gels: Supports hydration without adding an oil phase.
Creams and lotions: Complements emollients and occlusives with water-binding support.
Cleansers: Adds a conditioning-oriented hydration story to rinse-off products.
Shampoos and conditioners: Supports conditioned feel and static-control concepts.

Quick Formulation Guide

Variable	Practical starting point
Use level	Leave-on (serums, creams, lotions): 1% – 5% Rinse-off (cleansers, shampoos): 1% – 3% Hair conditioners: 1% – 3%
Phase	Water-soluble — add directly to the water phase. Can be added before heating (good heat stability) but avoid temperatures over 75°C . For heat-sensitive formulas, add during cool-down at ≤ 40°C .
PH	Stable across a broad pH range — optimal formulation pH 4.5 – 7.0 (ideally 5.0 – 6.0) .
Electrolytes	Treat Sodium PCA as an ionic input when selecting thickeners and surfactant systems.
Preservation	Count the water introduced by the raw material and preserve the complete finished formula.

Recommended Pairings

Pairing	Concept value	Example direction
Glycerin	Combines two familiar humectants with different sensory contributions.	Hydrating toner or body lotion.
Betaine	Adds osmolyte and conditioning support.	Low-tack essence or shampoo.
Sodium Hyaluronate	Adds polymeric hydration and slip.	Layered-hydration serum.
Panthenol	Adds humectant and conditioning support for skin or hair.	Comfort-focused lotion or scalp serum.
Urea	Builds an NMF-inspired hydration system.	Hand, foot or body-care emulsion.