A water-soluble Provitamin B5 powder for moisturizing, soothing and conditioning skin, hair and personal-care formulations.
- 99% DL-Panthenol for controlled bench evaluation and scalable formulation work
- Supports softer-feeling skin and smoother, more manageable-looking hair
- Water-soluble white crystalline powder for serums, creams, shampoos and conditioners
Product Specifications
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Specification |
Product detail |
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Product name |
DL-Panthenol / Provitamin B5 Powder |
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INCI name |
Panthenol [R1] |
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CAS number |
16485-10-2 [R2] |
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Molecular formula |
C9H19NO4 [R2] |
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Molecular weight |
205.25 g/mol [R2] |
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Assay |
99% |
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Appearance |
White crystalline powder |
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Solubility |
Soluble in water and alcohol; not soluble in oils [R4–R7] |
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Pack sizes |
100 g, 250 g, 500 g, 1Kg ; larger requirements by quotation |
Key Benefits
Moisture-supporting humectant. Panthenol helps water-based formulas support a softer, more comfortable skin feel and is widely used in moisturizers, serums and cleansers. [R3, R8–R9]
Skin-conditioning support. Panthenol-containing finished formulas have been studied for hydration and barrier-related measures. Performance depends on use level, vehicle, preservation and the complete formula. [R8–R9]
Hair-conditioning versatility. Panthenol is used in shampoos, conditioners, masks and leave-on products to support softness, manageability, shine and a smoother hair feel. Mechanistic work has also examined tensile properties in treated hair fibers. [R3, R10]
Easy fit for many water-based systems. The crystalline powder dissolves readily in water, giving formulators control over the active level without adding the carrier load of a diluted liquid grade.
Why Formulators Choose DL-Panthenol
DL-Panthenol is the racemic form containing D- and L-Panthenol. Both forms contribute humectant properties, while the D form is the enantiomer converted to pantothenic acid. This stable powder format is practical when a compact, high-assay raw material is preferred over a 50% or 75% aqueous solution. It works across skin care, hair care and cleansing products, making it useful for laboratories that want one familiar conditioning active for several development programs.
Typical Applications
- Hydrating facial serums, toners, gels and gel-creams
- Daily moisturizers, hand creams and body lotions
- Sensitive-skin and after-sun cosmetic care without drug claims
- Shampoos, conditioners, hair masks and detangling products
- Leave-in sprays, scalp serums and styling products
- Body washes, facial cleansers and other rinse-off systems
Quick Formulation Guide
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Formulation field |
Buyer guidance |
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Typical use level |
0.5–5% in cosmetic formulations [R4–R5] |
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Phase |
Water phase, or a separately prepared aqueous concentrate |
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Incorporation |
Pre-dissolve in water and mix until clear and uniform. It may be added to the water phase or during cool-down when the process and preservation system permit. |
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pH |
4-6 |
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Sensory control |
Higher use levels can increase tack or affect viscosity. Screen the lowest level that meets the product brief. |
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Hygroscopic handling |
Weigh promptly, minimize exposure to humid air and close the container tightly after use. |
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Compatibility / stability |
Check clarity, color, odor, pH, viscosity, preservation and active retention through stability testing. |
|
Storage |
Keep tightly closed in a cool, dry place protected from moisture and direct light. |
Why Source From Us
- Start with samples scale to bulk orders – one supplier from trial to production: Validate with lab samples, then scale to commercial volumes – same quality, same team. No re-qualification, no project delays.
- Formulation support that actually helps – not just a data sheet: We give you hands-on guidance on solubility, temperature, pH, and compatibility. A real formulation partner, not a catalog.
- Reliable supply chain – consistent quality, on-time delivery, batch after batch: Own manufacturing facilities plus long-term partnerships with audited upstream producers ensure batch-to-batch consistency. Full documentation with every shipment. No "sample passes, bulk fails"
- Export-ready documentation – compliance, customs, cleared:Complete technical documentation packages – COA, MSDS, TDS, stability data – batch-specific and regulatory-ready. We handle the paperwork so your compliance and procurement teams can focus on formulation
Recommended Ingredient Pairings
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Recommended ingredient |
Why it pairs well |
Product concept |
Compatibility note |
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Combines moisturization and skin-conditioning support in water-based formulas |
Hydrating daily serum or barrier-focused gel-cream |
Both are water-soluble; validate pH, sensory feel and preservation |
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|
Adds film-forming hydration and surface-smoothing value |
Multi-humectant serum or lightweight moisturizer |
Control total humectant load to avoid excessive tack |
|
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Supports a gentle, comfort-focused cosmetic concept |
Sensitive-skin toner, cream or after-sun care |
Respect allantoin solubility and processing limits |
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Hydrolyzed Protein |
Extends conditioning and manageability positioning for hair care |
Repair-focused conditioner, mask or leave-in spray |
Check charge, odor, color and preservative compatibility |
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BTMS Conditioning Emulsifier |
Provides cationic conditioning structure for rinse-off and leave-on hair systems |
Conditioner, hair mask or cream leave-in |
Follow the BTMS grade supplier process and validate deposition, viscosity and rinse feel |
Scientific Evidence Snapshot
Panthenol is used in cosmetics as a humectant and skin- and hair-conditioning ingredient. Controlled finished-formula studies have reported improvements in skin hydration and barrier-related measurements, while newer hair-fiber research has examined increases in break stress and elastic modulus after panthenol treatment. These findings support careful moisturization and conditioning claims. [R3, R8–R10]
Research & References
[R1] European Commission CosIng — PANTHENOL
[R2] PubChem — DL-panthenol, CID 4678
[R3] Cosmetic Ingredient Review — Panthenol family safety assessment
[R4] MakingCosmetics — Provitamin B5 Powder formulation guide
[R8] Camargo et al. — Skin moisturizing effects of panthenol formulations
[R10] Marsh et al. — Strengthening benefits of panthenol for hair
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