Acetyl Octapeptide-3 (SNAP-8) Cosmetic Grade Peptide

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✅ Cosmetic Grade Purity
✅ COA / TDS / MSDS Available
✅ 1g Sample to Bulk Supply
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Acetyl Octapeptide-3 99% Powder is a concentrated cosmetic peptide for measured development of serums, eye-area products, gels and emulsions focused on the visible appearance of expression lines. Its powder format gives formulators direct control over the active level and avoids confusing a dilute commercial solution with pure peptide dosing. Choose a practical paid trial size for bench work, request current grade documents for specification review, or submit your quantity, destination and technical requirements for bulk supply.

99% powder for low-dose, active-basis formulation work
Supports products designed to soften the look of expression lines and promote smoother-looking skin
Suitable for water-based serums, eye-area gels, emulsions and targeted age-support products
Practical gram-scale trial packs with a clear path to pilot and bulk purchasing

Product Specifications

Property	Product information
Product name	Acetyl Octapeptide-3 99% Powder
INCI name	Acetyl Octapeptide-3
Common reference name	SNAP-8 peptide
CAS number	868844-74-0 [R1]
Commercial form	Powder
Purity or assay	99% merchant-confirmed grade
Ingredient family	Synthetic expression-line cosmetic peptide
Intended use	Professional cosmetic formulation and measured small-batch development

Key Benefits

Helps soften the look of expression lines--Selected for formulas designed to reduce the visible prominence of expression-related lines, especially in targeted facial-care concepts. Use cosmetic appearance language for the finished product rather than drug or injection comparisons. [R5-R6]
Supports smoother-looking facial skin--Useful in age-support formulas where a smoother, more refined surface appearance is a central consumer benefit. Finished-product performance depends on the complete formula, delivery system and validated use level.
Supports a rested and refreshed appearance--Provides a focused peptide direction for products intended to make repeated-expression areas look less tense and more refreshed, while keeping claims within a cosmetic appearance scope.

Why Formulators Choose Acetyl Octapeptide 3

High active concentration allows precise powder-to-finished-formula calculations at very low use levels.
A measured stock solution makes milligram-scale dosing easier to reproduce across prototypes.
The peptide fits premium eye-area, forehead, facial-serum and targeted age-support product briefs.
Powder sourcing lets laboratories compare assay, identity and impurity information directly on the current COA.

Typical Applications

Targeted facial serum--Lightweight expression-line and smoother-looking-skin positioning
Eye-area serum or gel--Low-tack, carefully preserved formulas for the appearance of crow’s-feet
Forehead or frown-line concentrate--Focused leave-on treatment-style cosmetic format without drug claims
Emulsion or gel cream--Daily age-support products with cool-down peptide addition
Hydrogel or mask essence--Short-contact or leave-on hydration systems requiring compatibility validation

Quick Formulation Guide

Parameter	Practical development guidance
Recommended starting point	Start at 0.01% active powder in the first bench prototype.
Typical working range	0.005-0.05% of active powder in the finished formula. [R2-R3]
Stock solution	Prepare a measured aqueous stock solution when direct weighing is impractical. A 0.5% stock is a useful first trial; confirm complete dissolution and clarity. [R1-R2]
Phase and incorporation	Dissolve in deionized water or an appropriate buffered aqueous portion, then add to the water-based system with gentle mixing.
Addition stage	Add during cool-down below 40 C to limit unnecessary heat exposure. [R3-R4]
Initial pH strategy	Begin around final pH 5.5-6.5, then confirm peptide stability, appearance and preservation in the complete formula. [R3-R4]
Compatibility checks	Check clarity, precipitation, odor, color and assay retention with electrolytes, acids, strong oxidizers, proteolytic enzymes and other active ingredients.

Recommended Ingredient Pairings

Recommended ingredient	Why it pairs well	Product concept	Compatibility note
Sodium Hyaluronate	Adds immediate hydration and supports elegant serum texture.	Hydrating expression-line serum	Choose molecular-weight grade and control hydration or dispersion.
Ectoin	Supports hydration and environmental-stress product concepts.	Barrier-support peptide essence	Confirm electrolyte load, clarity and full-formula stability.
Acetyl Hexapeptide-8	Creates a multi-peptide expression-line concept with a distinct but related peptide.	Targeted eye or forehead serum	Do not assume additive efficacy; verify total peptide dose and stability.
Palmitoyl Tripeptide-5	Adds a complementary firming and elasticity appearance direction.	Multi-pathway age-support emulsion	Validate solubilization, pH and preservation for both supplied grades.

Scientific Evidence Snapshot

Acetyl Octapeptide-3 is an eight-residue cosmetic peptide associated with SNAP-25-inspired expression-line concepts. Analytical research confirms that the peptide can be identified and quantified by LC-MS/MS, supporting its relevance to cosmetic quality control. Published reviews discuss visible wrinkle-depth findings, but much of the specific performance evidence originates from supplier studies or finished multi-ingredient systems. Formulators should therefore validate the complete product rather than treating raw-material identity as proof of finished-formula performance. [R5-R6]

Research and References

[R1] Cayman Chemical Acetyl Octapeptide-3 technical record

[R2] ExperChem Acetyl Octapeptide-3 Product Information

[R3] LandNutra Acetyl Octapeptide-3 Powder

[R4] TCS Peptides SNAP-8 Acetyl Octapeptide-3

[R5] Ji et al Method development for Acetyl Octapeptide-3 analysis

[R6] Veiga et al Anti-aging peptides for advanced skincare

Frequently Asked Questions

Is 3-10% the correct dose for this powder?

No. That range usually refers to a highly diluted commercial peptide solution. For 99% active powder, typical comparable guidance is 0.005-0.05% of the finished formula. [R2-R3]

How should I weigh such a low use level?

Use an analytical balance or prepare a verified aqueous stock solution. Record the stock concentration, batch calculation, preparation date and preservation approach.

Can it be added to a hot emulsion?

Add it during cool-down, preferably below 40 C, after the main emulsion has formed. [R3-R4]

Can it be used with acids or Vitamin C?

Compatibility depends on acid type, final pH, oxidation risk and the complete system. Begin with a separate aqueous stock, avoid extreme pH, and verify stability analytically when the project requires it.

Is Acetyl Octapeptide-3 a Botox replacement?

No. It is a cosmetic raw material for topical formulation. Finished-product claims should remain focused on the visible appearance of expression lines and smoother-looking skin.

What should bulk buyers include in an inquiry?

Provide target quantity, destination, required specification, documentation needs, application format and desired purchasing timeline.

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Product: Acetyl Octapeptide-3 (SNAP-8) Cosmetic Grade Peptide

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Acetyl Octapeptide-3 (SNAP-8) Cosmetic Grade Peptide