PDRN / Sodium DNA Powder 99% (Polydeoxyribonucleotide)

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A high-assay Sodium DNA powder for skin-conditioning, hydration and age-support formulas, with practical paid trial sizes and bulk sourcing support.

• Supports development of hydrated, plumper-looking and well-conditioned skin-care formulas.

• Useful in serums, ampoules, creams, masks and other water-rich leave-on products.

• Powder format gives formulators control over concentration and carrier choice.

• Online sizes: 500 mg/1 g / 5 g / 10 g / 25 g; larger quantities by bulk inquiry.
Product Specifications / Key Facts

Item	Information
INCI name	Sodium DNA [R2]
Common names	PDRN; Polydeoxyribonucleotide; DNA-Na; Sodium DNA
Purity / assay	≥99%
Ingredient family	Nucleotide / DNA-derived cosmetic active
Typical formulation behavior	Water-compatible [R3–R5]

Key Benefits

Supports Hydrated, Plumper-Looking Skin: Sodium DNA is used in water-rich formulas designed to support moisture retention and leave skin looking hydrated and comfortably conditioned. [R2–R3]

Helps Build a Smoother, Better-Conditioned Skin Appearance: Sodium DNA is used in serums, masks and creams designed for a smoother, softer and better-conditioned skin appearance. [R3]

Useful for Barrier- and Comfort-Focused Formulas: PDRN research includes skin-barrier and cellular-response endpoints, supporting its use in formulas designed for skin comfort and a healthier-looking barrier. [R6–R7]

Adds Age-Support Relevance to Advanced Skincare: PDRN research includes fibroblast and collagen-related pathways, making Sodium DNA relevant to topical age-support formula development. [R7–R8]

Typical Applications

• Hydrating and age-support facial serums

• Ampoules and concentrated water-based essences

• Skin-comfort and barrier-support creams or gel-creams

• Sheet-mask essences and leave-on masks

• Eye-area hydration and smoothing formulas

• Multi-active systems with humectants, soothing agents and peptides

Recommended Ingredient Pairings

Recommended Ingredient	Why It Pairs Well	Product Concept
Sodium Hyaluronate	Adds humectancy and serum/gel support.	Hydrating PDRN serum or ampoule
Panthenol	Adds conditioning and comfort.	Skin-comfort serum or cream
Ectoin	Adds hydration and environmental-stress support.	Resilience and hydration serum
Beta-Glucan	Supports hydration and comfort.	Soothing mask essence or serum
Niacinamide	Adds barrier and tone-evening support.	Daily age-support serum
Copper Tripeptide-1	Adds a complementary peptide active.	Premium peptide + PDRN serum

Quick Formulation Guide

Decision Point	Practical Buyer Guidance
Use level	0.01%-3%
Phase / solubilization	Freely soluble in water. [R3–R5]
pH environment regulation	Sodium DNA is most stable in neutral to slightly alkaline aqueous solutions with a pH range of 6.0 – 8.0.
Compatibility	Screen the full active/preservative/electrolyte system; watch for haze, precipitation, viscosity change or loss of clarity.
Storage	Sodium DNA powder is hygroscopic and should be stored in tightly sealed containers, protected from light, moisture, and heat. Recommended storage temperature: below 30°C for short-term, or 2–8°C for long-term storage (over 3 months) to maximize stability

Research & References

Sodium DNA is used as a skin-conditioning cosmetic ingredient. PDRN research includes skin-barrier, fibroblast and collagen-related biology, supporting interest in age-support and skin-comfort formulas. [R2][R6–R8]

[R2] SpecialChem — SODIUM DNA: INCI Ingredient

[R3] HTL Biotechnology — Sodium DNA

[R6] Lee et al. (2023) — Analysis of Skin Regeneration and Barrier-Improvement Efficacy of PDRN

[R7] Shin et al. (2023) — PDRN effects in human skin keratinocytes and fibroblasts

[R8] Khan et al. (2022) — Polydeoxyribonucleotide: A promising skin anti-aging agent

Frequently Asked Questions

What is PDRN in a cosmetic raw material?

PDRN is a market term for polydeoxyribonucleotide DNA-fragment materials; Sodium DNA is a common cosmetic INCI used for this type of ingredient.

Is Sodium DNA the same as every PDRN powder?

Not necessarily. Commercial grades can differ in source, molecular-weight distribution, fragment length, assay method and quality controls. Compare the exact grade documents before scale-up.

What does 99% mean for this product?

This SKU is offered at 99% assay/purity. Confirm the analytical method and basis on the current specification or lot document.

What are the main cosmetic uses?

Common formats include serums, ampoules, masks and creams for hydration, conditioning, smoother-looking skin and age-support care.

What use level should I start with?

Start from the current TDS for the exact grade because molecular weight, assay basis and product form affect dosing and formula behavior.

Is Sodium DNA water soluble?

Commercial Sodium DNA powders are commonly used in water-rich systems. Confirm complete dissolution, clarity and viscosity with the selected grade. [R3–R5]

Can the raw powder be applied directly to skin?

No. This is a concentrated cosmetic raw material for measured formulation, not direct skin application, injection, ingestion or medical use.

How do I order trial and bulk quantities?

Choose 1–100 g for formulation and development. For larger quantities, send target volume, destination, specification and documentation needs for a bulk quotation.

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Product: PDRN / Sodium DNA Powder 99% (Polydeoxyribonucleotide)

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PDRN / Sodium DNA Powder 99% (Polydeoxyribonucleotide)