A high-purity, low-color curcumin derivative for premium brightening and antioxidant cosmetic formulation. Tetrahydrocurcumin (THC) is the hydrogenated derivative of curcumin. This 98% white-to-off-white powder is designed for advanced cosmetic R&D where antioxidant defense, visible tone refinement and reduced yellow-color burden are important formulation goals.
- 98% Tetrahydrocurcumin powder for measured cosmetic formulation.
- Strong antioxidant activity is supported by comparative laboratory research. [R5]
- Preclinical research supports anti-melanogenic and photoaging-focused development. [R3–R4]
- Paid trial sizes and bulk inquiry support evaluation from bench work to scale-up.
Product Specifications / Key Facts
|
Property |
Product Information |
|
Product Name |
Tetrahydrocurcumin |
|
Common Abbreviation |
THC |
|
Commercial Form |
White to off-white powder |
|
Purity / Assay |
98% |
|
INCI |
TETRAHYDROCURCUMIN |
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CAS Number |
36062-04-1 [R1] |
|
Molecular Formula / MW |
C21H24O6 / 372.4 g/mol [R1] |
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Ingredient Family |
Hydrogenated curcumin derivative / polyphenol antioxidant |
Key Benefits
Supports antioxidant defense — Hydrogenated curcumin derivatives, including Tetrahydrocurcumin, showed strong radical-scavenging and lipid-oxidation protection in comparative laboratory models. [R5]
Supports brightening and even-looking-tone concepts — THC reduced melanin production and melanogenesis-related enzyme expression in a stressed melanocyte model. [R3]
Relevant to photoaging-focused formulation — In a UV-induced mouse model, THC improved multiple photoaging-related appearance and molecular parameters. [R4]
Cleaner color profile than curcumin — The hydrogenated structure removes the intense conjugated yellow chromophore associated with curcumin, and 98% is commonly supplied as white to off-white powder. [R1,R7]
Suitable for advanced delivery-system development — Nanoemulsion and lipidic-nanostructure studies show that delivery architecture can materially influence topical deposition and performance. [R3,R6]
Why Formulators Choose Tetrahydrocurcumin
Tetrahydrocurcumin gives formulators a way to work with curcumin-related polyphenol chemistry without the same intense yellow color burden. Its antioxidant and melanogenesis research is attractive for premium tone-care and well-aging products, but the ingredient is not a simple water-phase active. Topical studies frequently use nanoemulsions, lipidic carriers or ointment systems, so carrier selection and delivery design are central to successful formulation. [R3,R6]
Typical Applications
- Brightening serums and creams
- Even-looking-tone emulsions
- Antioxidant / environmental-stress formulations
- Photoaging-focused night treatments
- Low-color curcuminoid skin-care systems
- Nanoemulsion, lipid-carrier or encapsulated active concepts
Quick Formulation Guide
|
Parameter |
Typical Formulation Guidance |
|
Solubility / Phase |
Do not treat THC as a conventional water-soluble powder.research formulations commonly rely on compatible organic solvents, lipid phases, PEG-type carriers, emulsions or nano-delivery systems. [R3,R6,R7] |
|
Processing |
Use the lowest practical thermal load for the selected carrier and minimize unnecessary air/light exposure during processing. |
|
Stability |
Monitor color and assay over stability. High purity and low initial color do not eliminate oxidation, crystallization or delivery-system instability risk. |
|
Delivery |
Nanoemulsion and lipidic-nanostructure studies demonstrate that carrier design can improve topical deposition / dermal delivery relative to simple systems. [R3,R6] |
|
Compatibility |
Evaluate oxidizing agents, strongly reactive redox systems, incompatible solvents and high-solid formulations carefully. Confirm solubility after cool-down and through storage. |
|
Packaging |
Use light-limiting, air-reducing packaging where appropriate and validate crystal formation, color and assay in the final pack. |
Quality Documents & Supply
Before production purchasing, review the current lot documentation for HPLC assay, identity, appearance, water content or loss on drying, residual solvents, related substances, storage and packaging requirements.
Scientific Evidence Snapshot
Tetrahydrocurcumin has a meaningful preclinical evidence base for antioxidant and tone-care research. In comparative antioxidant assays, hydrogenated curcumin derivatives showed stronger activity than curcumin in several models. [R5] In melanocyte and keratinocyte models, THC reduced stress-related melanin production and oxidative damage; a lecithin nanoemulsion also improved topical delivery characteristics. [R3] A UV-induced mouse photoaging study reported improvements in skin appearance, extracellular-matrix and melanogenesis-related pathways. [R4]
Recommended Ingredient Pairings
|
Recommended Ingredient |
Why It Pairs Well |
Product Concept |
|
Adds barrier and tone-care support. |
Brightening + barrier serum / cream |
|
|
Adds a second brightening pathway. |
Dual-brightening serum |
|
|
Adds water-phase vitamin C derivative and antioxidant/tone-care value. |
Multi-antioxidant brightening system |
|
|
Adds oil-phase antioxidant support. |
Lipid-based antioxidant cream |
|
|
Adds polyphenolic antioxidant-network potential. |
Advanced antioxidant serum |
|
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Adds hydration and skin feel. |
Hydrating brightening emulsion |
Research & References
[R1] PubChem — Tetrahydrocurcumin (CID 124072): CAS 36062-04-1; C21H24O6; MW 372.4.
[R2] CosIng-derived record — TETRAHYDROCURCUMIN, antioxidant cosmetic function.
[R5] Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives.
[R6] Assay and Dermatokinetics of Tetrahydrocurcumin Lipidic Nanostructures.
Frequently Asked Questions
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