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Tetrahydrocurcumin 98% Powder

Tetrahydrocurcumin 98% Powder

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Regular price $16.90 USD
Regular price $0.00 USD Sale price $16.90 USD
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  • ✅ Cosmetic Grade Purity
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A high-purity, low-color curcumin derivative for premium brightening and antioxidant cosmetic formulation. Tetrahydrocurcumin (THC) is the hydrogenated derivative of curcumin. This 98% white-to-off-white powder is designed for advanced cosmetic R&D where antioxidant defense, visible tone refinement and reduced yellow-color burden are important formulation goals.

  • 98% Tetrahydrocurcumin powder for measured cosmetic formulation.
  • Strong antioxidant activity is supported by comparative laboratory research. [R5]
  • Preclinical research supports anti-melanogenic and photoaging-focused development. [R3–R4]
  • Paid trial sizes and bulk inquiry support evaluation from bench work to scale-up.

Product Specifications / Key Facts

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Product Information

Product Name

Tetrahydrocurcumin

Common Abbreviation

THC

Commercial Form

White to off-white powder

Purity / Assay

98%

INCI

TETRAHYDROCURCUMIN

CAS Number

36062-04-1 [R1]

Molecular Formula / MW

C21H24O6 / 372.4 g/mol [R1]

Ingredient Family

Hydrogenated curcumin derivative / polyphenol antioxidant

 

Key Benefits

Supports antioxidant defense — Hydrogenated curcumin derivatives, including Tetrahydrocurcumin, showed strong radical-scavenging and lipid-oxidation protection in comparative laboratory models. [R5]

Supports brightening and even-looking-tone concepts — THC reduced melanin production and melanogenesis-related enzyme expression in a stressed melanocyte model. [R3]

Relevant to photoaging-focused formulation — In a UV-induced mouse model, THC improved multiple photoaging-related appearance and molecular parameters. [R4]

Cleaner color profile than curcumin — The hydrogenated structure removes the intense conjugated yellow chromophore associated with curcumin, and 98% is commonly supplied as white to off-white powder. [R1,R7]

Suitable for advanced delivery-system development — Nanoemulsion and lipidic-nanostructure studies show that delivery architecture can materially influence topical deposition and performance. [R3,R6]

Why Formulators Choose Tetrahydrocurcumin

Tetrahydrocurcumin gives formulators a way to work with curcumin-related polyphenol chemistry without the same intense yellow color burden. Its antioxidant and melanogenesis research is attractive for premium tone-care and well-aging products, but the ingredient is not a simple water-phase active. Topical studies frequently use nanoemulsions, lipidic carriers or ointment systems, so carrier selection and delivery design are central to successful formulation. [R3,R6]

Typical Applications

  • Brightening serums and creams
  • Even-looking-tone emulsions
  • Antioxidant / environmental-stress formulations
  • Photoaging-focused night treatments
  • Low-color curcuminoid skin-care systems
  • Nanoemulsion, lipid-carrier or encapsulated active concepts

Quick Formulation Guide

Parameter

Typical Formulation Guidance

Solubility / Phase

Do not treat THC as a conventional water-soluble powder.research formulations commonly rely on compatible organic solvents, lipid phases, PEG-type carriers, emulsions or nano-delivery systems. [R3,R6,R7]

Processing

Use the lowest practical thermal load for the selected carrier and minimize unnecessary air/light exposure during processing.

Stability

Monitor color and assay over stability. High purity and low initial color do not eliminate oxidation, crystallization or delivery-system instability risk.

Delivery

Nanoemulsion and lipidic-nanostructure studies demonstrate that carrier design can improve topical deposition / dermal delivery relative to simple systems. [R3,R6]

Compatibility

Evaluate oxidizing agents, strongly reactive redox systems, incompatible solvents and high-solid formulations carefully. Confirm solubility after cool-down and through storage.

Packaging

Use light-limiting, air-reducing packaging where appropriate and validate crystal formation, color and assay in the final pack.

Quality Documents & Supply

Before production purchasing, review the current lot documentation for HPLC assay, identity, appearance, water content or loss on drying, residual solvents, related substances, storage and packaging requirements.

Scientific Evidence Snapshot

Tetrahydrocurcumin has a meaningful preclinical evidence base for antioxidant and tone-care research. In comparative antioxidant assays, hydrogenated curcumin derivatives showed stronger activity than curcumin in several models. [R5] In melanocyte and keratinocyte models, THC reduced stress-related melanin production and oxidative damage; a lecithin nanoemulsion also improved topical delivery characteristics. [R3] A UV-induced mouse photoaging study reported improvements in skin appearance, extracellular-matrix and melanogenesis-related pathways. [R4] 

Recommended Ingredient Pairings

Recommended Ingredient

Why It Pairs Well

Product Concept

Niacinamide

Adds barrier and tone-care support.

Brightening + barrier serum / cream

Alpha-Arbutin

Adds a second brightening pathway.

Dual-brightening serum

Ascorbyl Glucoside

Adds water-phase vitamin C derivative and antioxidant/tone-care value.

Multi-antioxidant brightening system

Tocopherol

Adds oil-phase antioxidant support.

Lipid-based antioxidant cream

Ferulic Acid

Adds polyphenolic antioxidant-network potential.

Advanced antioxidant serum

Sodium Hyaluronate

Adds hydration and skin feel.

Hydrating brightening emulsion

 

Frequently Asked Questions

What is Tetrahydrocurcumin?

Tetrahydrocurcumin is the hydrogenated derivative of curcumin. It retains polyphenol antioxidant chemistry while having a much lower-color appearance than conventional curcumin.

What is the CAS number of Tetrahydrocurcumin?

Tetrahydrocurcumin is CAS 36062-04-1 with molecular formula C21H24O6. [R1]

Why is Tetrahydrocurcumin white while curcumin is yellow?

Hydrogenation changes the conjugated structure responsible for curcumin’s intense yellow chromophore, so high-purity THC is commonly white to off-white.

Is Tetrahydrocurcumin water soluble?

 It should not be treated as a conventional water-soluble active. Use compatible solvent, lipid or delivery-system strategies and confirm real solubility in the selected base.

Is Tetrahydrocurcumin clinically proven for skin brightening?

Current evidence includes strong cell, delivery-system and animal research.

Can Tetrahydrocurcumin be combined with Niacinamide or Alpha-Arbutin?

Yes as formulation concepts, but the actives have different solubility and stability needs. Validate phase architecture, pH and long-term stability in the finished system.

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