A next-generation antioxidant for premium photoaging and environmental-stress skin-care formulations. Acetyl Zingerone is a multifunctional phenolic antioxidant designed around the zingerone scaffold. This 98% white powder gives formulators a concentrated active for serums, creams, emulsions and advanced antioxidant systems where visible photoaging, uneven tone and oxidative-stress defense are key product goals.
- 98% Acetyl Zingerone powder for professional cosmetic formulation.
- Human vehicle-controlled evidence supports visible improvement in wrinkles, pigmentation and redness at 1% topical use. [R3]
- Mechanistic research supports free-radical control, singlet-oxygen quenching and photostability. [R6]
Product Specifications / Key Facts
|
Property |
Product Information |
|
Product Name |
Acetyl Zingerone |
|
Commercial Form |
White powder |
|
Purity / Assay |
98% |
|
INCI |
ACETYL ZINGERONE |
|
CAS Number |
30881-23-3 [R1–R2] |
|
Molecular Formula / MW |
C13H16O4 / 236.26 g/mol [R1] |
|
UNII |
V9D92S9YE5 [R1] |
|
Ingredient Family |
Phenolic diketone / multifunctional antioxidant active |
Key Benefits
Supports visible photoaging improvement — In a randomized double-blind vehicle-controlled study, a 1% Acetyl Zingerone cream used twice daily for eight weeks significantly improved wrinkle severity/volume, pigment intensity and redness compared with vehicle. [R3]
Provides multi-pathway antioxidant defense — In-vitro research shows free-radical scavenging, singlet-oxygen quenching, peroxynitrite scavenging and reduction of UVA-induced intracellular ROS. [R6]
Adds photostable antioxidant support — Acetyl Zingerone showed greater molecular photostability than α-tocopherol in a solar-simulated UV study, supporting use in day-care and photoaging-focused formulas. [R6]
Supports extracellular-matrix-focused anti-aging concepts — Reconstructed-skin and enzyme research reported MMP inhibition and favorable modulation of genes related to extracellular-matrix integrity. [R7]
Fits advanced antioxidant + vitamin C systems — A randomized study using 1% AZ with 5% tetrahexyldecyl ascorbate reported better wrinkle, pigment and redness outcomes than THDA alone. [R4]
Why Formulators Choose Acetyl Zingerone
Acetyl Zingerone is unusual among cosmetic antioxidants because it combines a defined small-molecule identity with both mechanistic and human clinical data. It is also positioned around photostability and several reactive-species pathways rather than a single radical-scavenging mechanism. For formulators, the practical challenge is phase design: the powder should be completely solubilized in a compatible oil/solvent architecture rather than treated as a simple water-soluble active.
Typical Applications
- Premium antioxidant serums and emulsions
- Photoaging and environmental-stress facial care
- Day creams and antioxidant-support sunscreen-adjacent formulas
- Uneven-tone and visible-redness appearance products
- Vitamin C derivative / multi-antioxidant systems
- Well-aging creams focused on texture, firmness and radiance
Quick Formulation Guide
|
Parameter |
Typical Formulation Guidance |
|
Use Level |
A 1% topical Acetyl Zingerone formulation has direct randomized vehicle-controlled human evidence for visible photoaging improvement. [R3] Treat 1% as an evidence-backed reference point, not a universal requirement;. |
|
Solubility / Phase |
Do not treat Acetyl Zingerone as a simple water-soluble powder. Use a compatible solvent, ester or oil/solvent system and verify complete dissolution before final emulsification or cool-down. |
|
Processing |
Maintain complete dissolution and avoid unnecessary prolonged heat. [R8] |
|
Compatibility |
Acetyl Zingerone can be paired with lipophilic vitamin C derivatives and other antioxidants, but validate the complete redox system rather than assuming automatic synergy. |
|
Photoprotection |
Acetyl Zingerone can support photoaging-defense concepts, but it is not a UV filter and does not replace sunscreen or SPF validation. |
|
Packaging |
Light-limiting and low-air-exposure packaging. |
Recommended Ingredient Pairings
|
Recommended Ingredient |
Why It Pairs Well |
Product Concept |
|
Direct clinical combination evidence with 1% AZ supports an advanced antioxidant/photoaging concept. |
AZ + THDA antioxidant serum |
|
|
Adds a conventional lipid-phase antioxidant pathway. |
Multi-antioxidant day cream |
|
|
Adds phenolic antioxidant-network potential. |
High-performance environmental-defense serum |
|
|
Adds barrier and tone-care support. |
Antioxidant + barrier serum |
|
|
Adds environmental-stress and hydration positioning. |
Urban-defense serum |
|
|
Provides an elegant emollient/oil phase for lipophilic antioxidant systems. |
AZ facial oil / emulsion |
Scientific Evidence Snapshot
Acetyl Zingerone has an unusually useful evidence ladder for a cosmetic antioxidant. In a randomized double-blind vehicle-controlled clinical study, 31 participants used a 1% AZ cream or vehicle twice daily for eight weeks; the AZ group showed significant reductions in wrinkle severity, wrinkle volume, pigment intensity and redness versus vehicle. [R3] A second randomized double-blind study found that adding 1% AZ to 5% tetrahexyldecyl ascorbate improved wrinkle severity, facial pigment and redness compared with THDA alone. [R4] Mechanistic studies support ROS control, singlet-oxygen quenching, photostability and reduction of delayed UV-induced DNA photoproduct formation. [R6] These data support next-generation antioxidant/photoaging positioning, but they do not make AZ a sunscreen, DNA-repair drug or substitute for finished-product UV protection.
Research & References
[R1] NIH NCATS / GSRS — Acetyl Zingerone: CAS 30881-23-3; C13H16O4; MW 236.2637; UNII V9D92S9YE5.
[R2] Korea Cosmetic Association — Acetyl Zingerone ingredient identity and cosmetic functions.
Frequently Asked Questions
You may also like
-
DDBD Diacetate 99 Percent Powder
Regular price From $39.90 USDRegular price$0.00 USDSale price From $39.90 USD -
Acetyl Octapeptide-3 (SNAP-8) Cosmetic Grade Peptide
Regular price From $39.90 USDRegular price$0.00 USDSale price From $39.90 USD -
GHK-Cu Blue Powder 99% | Copper Tripeptide-1
Regular price From $14.90 USDRegular price$0.00 USDSale price From $14.90 USD -
PDRN / Sodium DNA Powder 99% (Polydeoxyribonucleotide)
Regular price From $14.90 USDRegular price$0.00 USDSale price From $14.90 USD -
Matrixyl 3000 Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7 Peptide Blend — 200 ppm Premix Liquid
Regular price From $19.90 USDRegular price$0.00 USDSale price From $19.90 USD -
Synthetic Melittin Powder 98%｜Cosmetic Grade Synthetic Bee Venom Peptide
Regular price From $49.00 USDRegular price$0.00 USDSale price From $49.00 USD -
Diglucosyl Gallic Acid 98% Powder
Regular price From $29.90 USDRegular price$0.00 USDSale price From $29.90 USD -
Tetrahydrocurcumin 98% Powder
Regular price From $16.90 USDRegular price$0.00 USDSale price From $16.90 USD
Request a Quote
Tell us your required quantity, destination country, and any documentation needs. We usually reply within 1 business day.