Hydroxytyrosol 99% High-Purity Liquid

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A concentrated polyphenol antioxidant for advanced anti-aging, photoaging-defense and soothing cosmetic formulation. Hydroxytyrosol is a defined catechol polyphenol naturally occurring in olives and olive-derived materials. This grade is supplied as a ≥99% high-purity, light-yellow viscous liquid that is miscible with water, giving formulators a highly concentrated active for serums, essences, creams and environmental-stress skin-care systems.

≥99% high-purity Hydroxytyrosol active.
Light-yellow viscous liquid with water-miscible formulation behavior.
Strong antioxidant / free-radical-scavenging identity for photoaging and environmental-stress concepts. [R1,R5]
Useful in soothing, skin-conditioning and well-aging cosmetic formulations. [R2]
Paid evaluation quantities and bulk inquiry support formulation from bench testing to scale-up.

Product Specifications / Key Facts

Property	Product Information
Product Name	Hydroxytyrosol
Commercial Form	High-purity concentrated liquid
Purity / Assay	≥99%
Appearance	Light-yellow viscous liquid
Solubility	Miscible with water
INCI	HYDROXYTYROSOL [R2]
CAS Number	10597-60-1 [R1]
Molecular Formula / MW	C8H10O3 / 154.16 g/mol [R1]
Ingredient Family	Catechol polyphenol / antioxidant active

Key Benefits

Supports antioxidant defense — Hydroxytyrosol is a potent polyphenol antioxidant that scavenges reactive species and is widely studied for oxidative-stress protection. [R1,R5]

Supports photoaging-focused cosmetic development — Recent preclinical skin research links Hydroxytyrosol with reduced UV-induced oxidative stress, matrix-degradation signaling and moisture-loss pathways. [R9]

Useful in firmness and elasticity concepts — Hydroxytyrosol has shown anti-collagenase / anti-elastase activity and fibroblast-protective effects in skin-relevant laboratory models. [R5]

Supports soothing and skin-conditioning positioning — Cosmetic ingredient references list Hydroxytyrosol for antioxidant, skin-conditioning and soothing functions. [R2]

Fits brighter, more even-looking tone concepts — A human dermocosmetic study using hydroxytyrosol-titrated olive extract reported improvement in pigmentation imaging, supporting cautious tone-care positioning. [R8]

Why Formulators Choose ≥99% Hydroxytyrosol Liquid

High-purity Hydroxytyrosol gives formulators a different level of control from olive extracts standardized to lower polyphenol concentrations. The ≥99% liquid format lets the formulator calculate Hydroxytyrosol active directly, while its water-miscible behavior supports aqueous and emulsion-based development. The main technical challenge is not identity but stability and delivery: Hydroxytyrosol can discolor or degrade through oxidation, and its hydrophilic character can limit passive skin permeation. [R6–R7]

Typical Applications

Antioxidant facial serums and essences
Photoaging and environmental-stress skin-care
Well-aging creams and emulsions
Soothing / sensitive-skin antioxidant products
Brightening and even-looking-tone systems
Advanced delivery systems such as niosomal or encapsulated Hydroxytyrosol concepts

Quick Formulation Guide

Parameter	Typical Formulation Guidance
Phase / Solubility	miscible with water. It can be introduced through the aqueous phase or a compatible pre-solution, while minimizing unnecessary exposure to air and heat.
Processing	Prefer moderate or cool-down processing where practical. Because Hydroxytyrosol is oxidation-sensitive, minimize prolonged heat, open-vessel aeration and strong light exposure.
Stability	Monitor color and assay over stability. A 2024 formulation study found that ethyl ascorbic acid reduced discoloration and that multi-antioxidant systems delayed Hydroxytyrosol degradation most effectively. [R7]
Delivery	Hydrophilicity can limit passive skin permeation; niosomal delivery significantly increased flux and skin retention versus simple Hydroxytyrosol solutions in ex-vivo human skin. [R6]
Compatibility	Evaluate oxidizers, transition-metal contamination, high-pH environments and other redox-active ingredients carefully. A compatible chelation/antioxidant strategy may help.
Packaging	Low-air-exposure, light-limiting packaging.

Quality Documents & Supply

Before production purchasing, review the current specification for HPLC assay, water content, appearance, pH where relevant, residual solvents or synthesis/extraction markers where applicable, oxidation-related impurities, storage and packaging requirements.

Recommended Ingredient Pairings

Recommended Ingredient	Why It Pairs Well	Product Concept
Ascorbyl Glucoside	Adds a water-compatible vitamin C derivative and complementary antioxidant / tone-care route.	Multi-antioxidant brightening serum
Niacinamide	Adds barrier, hydration and tone-care support.	Antioxidant + barrier serum
Tocopherol	Adds oil-phase antioxidant support to emulsions.	Dual-phase antioxidant cream
Ferulic Acid	Adds polyphenolic antioxidant-network potential.	High-performance antioxidant serum
Ectoin	Adds environmental-stress and hydration positioning.	Urban-defense / sensitive-skin serum
Sodium Hyaluronate	Adds hydration and skin feel.	Hydrating antioxidant essence

Scientific Evidence Snapshot

In human dermal fibroblasts, Hydroxytyrosol reduced oxidative-stress-related ROS and showed moderate inhibition of elastase and collagenase, supporting skin-aging research relevance. [R5] Delivery research demonstrates that simple aqueous Hydroxytyrosol has relatively low passive skin permeation, while a niosomal system markedly increased flux and skin retention. [R6] A 2024 formulation study also documented practical stability strategies for Hydroxytyrosol creams and hydrogels. [R7] Human pigmentation data are available for a Hydroxytyrosol-titrated olive-extract formulation. [R8]

Research & References

[R1] PubChem — Hydroxytyrosol (CID 82755): CAS 10597-60-1; C8H10O3; MW 154.16.

[R2] SpecialChem — HYDROXYTYROSOL cosmetic INCI and function profile.

[R3] SpecialChem / SpringPharma — HTOrigin® Hydroxytyrosol 99% Liquid, comparable high-purity liquid cosmetic grade.

[R4] U.S. FDA — GRAS Notice 1182 response letter describing Hydroxytyrosol as a slightly yellow viscous liquid.

[R5] Li H, et al. Hydroxytyrosol and skin-ageing-related elastase/collagenase/ROS research.

[R6] Niosomal formulation of Hydroxytyrosol for enhanced skin delivery.

[R7] Hydroxytyrosol permeability comparisons and strategies to improve stability in formulations.

[R8] Clinical study of topical antioxidants including Hydroxytyrosol-titrated olive extract.

Frequently Asked Questions

What is Hydroxytyrosol?

Hydroxytyrosol is a catechol polyphenol antioxidant naturally found in olives and related olive materials. The molecule itself is identified as CAS 10597-60-1.

Is this an olive extract?

No. This SKU is positioned as ≥99% high-purity Hydroxytyrosol liquid, not as an olive extract standardized to a lower Hydroxytyrosol percentage.

Why is a ≥99% Hydroxytyrosol product a liquid?

High-purity Hydroxytyrosol is commercially available as a light-yellow viscous liquid; FDA food-ingredient documentation and current cosmetic supplier data describe similar high-purity liquid forms. [R3–R4]

Is Hydroxytyrosol water soluble?

This grade is confirmed as miscible with water. Current high-purity commercial references also report strong water/alcohol compatibility. [R3]

What use level should I start with?

Use the current grade TDS and your target finished-product active level.

Why can Hydroxytyrosol formulations discolor?

The catechol structure is oxidation-sensitive. Heat, air, metal contamination and the antioxidant environment can influence color and assay stability. [R7]

Does Hydroxytyrosol penetrate skin well?

Simple Hydroxytyrosol solutions show limited passive permeation because the molecule is hydrophilic; niosomal systems have been shown to improve skin flux and retention. [R6]