A high-purity brightening peptide for advanced even-looking-tone cosmetic development. Oligopeptide-68 is a 12-amino-acid peptide used in premium brightening systems and pigmentation-pathway research. This 98% powder provides a concentrated format for serums, emulsions and targeted tone-care products.
- 98% Oligopeptide-68 powder for professional cosmetic formulation.
- Designed for brightening, radiance and more even-looking skin-tone concepts.
- Peptide-based positioning offers a differentiated route from conventional small-molecule brightening actives.
Product Specifications / Key Facts
|
Property |
Product Information |
|
Product Name |
Oligopeptide-68 |
|
Commercial Form |
Powder |
|
Purity / Assay |
98% |
|
INCI |
OLIGOPEPTIDE-68 |
|
Peptide Length |
12 amino acids |
|
Reference Sequence |
GRGDYIWSLDTQ [R1–R3] |
|
Reference Chemical Identity |
CAS 1206525-47-4 for the free-peptide identity [R1–R3] |
|
Ingredient Family |
Synthetic cosmetic oligopeptide / brightening peptide |
Key Benefits
Supports brighter, more even-looking skin — Oligopeptide-68 is used in cosmetic systems designed to influence pigmentation-related signaling and reduce the appearance of uneven tone. [R4–R7]
Targets visible discoloration through a peptide-based approach — The ingredient is commonly positioned around MITF/tyrosinase-pathway modulation, giving formulators a different technical story from direct small-molecule tyrosinase inhibitors.
Fits premium multi-active brightening systems — Human studies have evaluated Oligopeptide-68 as part of multi-active depigmenting formulas that improved melasma-related clinical endpoints. [R4–R5] These results support formula-level relevance but do not isolate the peptide's individual effect.
Supports sophisticated peptide-led product positioning — The 98% powder format allows controlled active loading and gives R&D teams flexibility to build their own aqueous, glycerin or delivery-system architecture.
Typical Applications
- Premium brightening serums and essences
- Even-looking-tone creams and emulsions
- Dark-spot appearance treatment products
- Peptide-based radiance concentrates
- Multi-active discoloration-care systems
Quick Formulation Guide
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Parameter |
Typical Formulation Guidance |
|
Solubility / Stock Solution |
Oligopeptide-68 is commonly handled through aqueous or water-compatible stock solution. |
|
Processing |
Add in a low-temperature stage after high-heat processing whenever practical. Avoid prolonged high heat, harsh shear and unnecessary exposure to strongly acidic or alkaline conditions. |
|
Compatibility |
Evaluate strong oxidizing agents, proteolytic enzymes, extreme pH, high electrolyte loads and complex preservation systems carefully. Confirm peptide stability and finished-product appearance over time. |
|
Preservation |
A peptide stock solution or finished aqueous formula still requires an appropriate preservation strategy. |
|
Packaging |
Use packaging that limits contamination and unnecessary heat/light exposure. |
Recommended Ingredient Pairings
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Recommended Ingredient |
Why It Pairs Well |
Product Concept |
|
Adds barrier and tone-care support through a different pathway. |
Peptide brightening serum |
|
|
Adds a complementary tyrosinase-focused route. |
Dual-action brightening essence |
|
|
Adds tone and texture-care value. |
Even-tone peptide serum |
|
|
Adds a complementary discoloration-care pathway. |
Advanced tone-correction serum |
|
|
Adds hydration and skin feel. |
Hydrating peptide essence |
|
|
Adds conditioning and comfort. |
Soothing brightening serum |
Scientific Evidence Snapshot
Oligopeptide-68 has been studied mainly in multi-active brightening systems. A randomized double-blind 12-week melasma study using formulas with diacetyl boldine and TGF-β1 biomimetic Oligopeptide-68 reported improved pigmentation outcomes. [R4] Another 12-week multi-active study containing Oligopeptide-68 reported clinical and reflectance-confocal improvement. [R5]
Research & References
[R2] Sigma-Aldrich / AA Blocks — Oligopeptide-68 98% reference product.
[R3] MedChemExpress — Oligopeptide-68 identity and sequence cross-check.
[R5] Reflectance Confocal Microscopy Assessment of the Depigmenting Agents Complex for Melasma Treatment.
Frequently Asked Questions
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