Palmitoyl Pentapeptide-4 (Matrixyl) Powder 98%

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✅ Cosmetic Grade Purity
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Palmitoyl Pentapeptide-4 98% Powder is a concentrated signal peptide for serums, eye products and emulsions focused on fine-line, firmness and texture care. Unlike a diluted premix, it gives direct control of active loading. Choose a paid evaluation pack, then request commercial quantities.

98% powder for controlled R&D and custom active loading.
For fine-line, firmness and skin-texture concepts.
Suitable for serums, eye products and emulsions.

Product Specifications

Property	Product Information
Product Name	Palmitoyl Pentapeptide-4
INCI Name	Palmitoyl Pentapeptide-4
Ingredient Type	Palmitoylated signal peptide / skin-conditioning active
Commercial Form	Powder
Assay	98%
Typical Product Formats	Leave-on serums, eye-care products, creams, lotions and gel creams
Use Category	Cosmetic formulation raw material for external-use finished products

Key Benefits

Visible fine-line care. Studied finished formulas support photoaged-skin and crow’s-feet appearance claims. [R3,R5]
Firmer, smoother-looking skin concepts. Fits briefs focused on firmness, elasticity and texture.
Precise low-level dosing. Gives formulators control of peptide loading without a fixed premix carrier.

Typical Applications

Precision peptide serums for visible fine-line and texture care
Eye creams and eye serums for crow’s-feet appearance
Firming moisturizers, gel creams and lightweight facial emulsions
Neck and décolletage age-support products

Quick Formulation Guide

Parameter	Practical Development Guidance
Typical active level	Evaluate approximately 3–50 ppm active (0.0003%–0.005%) in the finished formula for comparable Pal-KTTKS systems. [R2–R5]
Recommended starting point	Start around 5 ppm active (0.0005%) for a first leave-on prototype. [R3,R5]
Weighing strategy	Do not weigh sub-milligram amounts on a standard balance. Use a validated stock and calculate from its confirmed peptide content.
Phase and addition	Add the validated stock or uniform dispersion to the aqueous system during cool-down. Pure palmitoylated powder can be difficult to dissolve directly in water. [R6]
Temperature strategy	Minimize unnecessary heat exposure and add after the main heat cycle once the batch is cool enough for the validated peptide stock.
pH strategy	Begin in a mildly acidic to near-neutral system, around pH 5.5–6.0, then verify appearance, assay retention and preservative performance in the complete formula.
Compatibility checks	Screen strong acids or bases, redox actives, high electrolyte loads, surfactants and chelating systems.
Packaging and stability	Use suitable protective packaging. Run accelerated and real-time stability, freeze–thaw and packaging-compatibility checks.

First Prototype Example

A 100 g batch at 5 ppm requires 0.5 mg active peptide, which is usually impractical to weigh directly. If a validated 0.05% stock contains 0.5 mg per gram, add 1.00 g stock and reduce the matching formula carrier by 1.00 g. Add during cool-down, begin near pH 5.5–6.0, mix until uniform and record pH, appearance and viscosity. Confirm stock-carrier and preservative compatibility before scaling.

Recommended Ingredient Pairings

Recommended Ingredient	Why It Pairs Well	Product Concept
Sodium Hyaluronate	Adds humectant hydration and serum slip.	Hydrating peptide serum
Niacinamide	Adds tone, texture and barrier-support value.	Daily multi-active serum
Ceramide NP	Adds barrier-lipid support to an age-support cream.	Peptide barrier cream
Panthenol	Adds conditioning and comfort-focused support.	Soothing firming lotion
Acetyl Hexapeptide-8 Solution	Creates a distinct multi-peptide expression-line concept.	Advanced peptide eye serum

Scientific Evidence Snapshot

A 12-week double-blind split-face study in 93 women evaluated a moisturizer containing pal-KTTKS and reported improvements in photoaged facial-skin endpoints. [R3] A later randomized study evaluated a 0.005% cream for crow’s-feet appearance. [R5] Laboratory work also found greater stability and skin distribution for palmitoyl-KTTKS than unmodified KTTKS in the tested model. [R4]