Retinal 99% Powder

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A high-purity retinaldehyde raw material for advanced anti-aging cosmetic formulation.
Retinal—also called retinaldehyde—is the aldehyde form of vitamin A and a direct precursor to retinoic acid. This 99% powder is intended for controlled R&D in premium night serums, creams and delivery systems where fine lines, texture, elasticity and tone are key goals. [R3–R6]

99% Retinal / Retinaldehyde powder for measured cosmetic formulation.
supports wrinkle-, texture-, hydration- and elasticity-focused age-support concepts. [R3–R5]
Distinct from retinol: retinal is one biochemical conversion step from retinoic acid.

Product Specifications / Key Facts

Property	Product Information
Product Name	Retinal / Retinaldehyde
Commercial Form	Powder
Purity / Assay	99%
INCI	RETINAL [R2]
CAS Number	116-31-4 [R1–R2]
Molecular Formula / MW	C20H28O / 284.4 g/mol [R1]
Identity	All-trans retinal / retinaldehyde
Ingredient Family	Vitamin A retinoid / retinoic-acid precursor

Key Benefits

Fine lines and wrinkles — Finished retinaldehyde creams have shown improvements in wrinkle-related and photoaging parameters. [R3–R4]

Smoother-looking texture — A randomized study found significant texture improvements with 0.05% and 0.1% retinaldehyde creams. [R3]

Elasticity and skin quality — Human studies report improvements in elasticity, hydration and other aging-related biophysical measures. [R3–R5]

Even-looking tone — The 0.1% group in the 2018 study improved melanin index; the 0.05% group did not, so tone claims should remain formula-specific. [R3]

Typical Applications

Night serums and age-support concentrates
Fine-line and texture-focused facial creams
Lipid-carrier or encapsulated retinal systems
Eye-area and premium retinoid products with validated stability

Quick Formulation Guide

Parameter	Typical Formulation Guidance
Use Level	about 0.01–0.10% [R3–R5]
Solubility / Phase	Retinal is lipophilic; pre-solubilize in a compatible solvent or lipid carrier[R8–R9]
Processing	Minimize heat and unnecessary exposure to strong light and air; cool-down or another low-temperature addition step is generally preferred when the system permits. [R6,R8]
Compatibility	Evaluate strong oxidizing/reducing systems, extreme pH, metal ions and other reactive ingredients through assay, color and odor stability testing.
Packaging	Opaque or UV-protective, low-air-exposure packaging is generally preferred for sensitive retinoid systems. [R6,R8]

Why Source From Us

Start with samples scale to bulk orders – one supplier from trial to production: Validate with lab samples, then scale to commercial volumes – same quality, same team. No re-qualification, no project delays.
Formulation support that actually helps – not just a data sheet: We give you hands-on guidance on solubility, temperature, pH, and compatibility. A real formulation partner, not a catalog.
Reliable supply chain – consistent quality, on-time delivery, batch after batch: Own manufacturing facilities plus long-term partnerships with audited upstream producers ensure batch-to-batch consistency. Full documentation with every shipment. No "sample passes, bulk fails"
Export-ready documentation – compliance, customs, cleared：Complete technical documentation packages – COA, MSDS, TDS, stability data – batch-specific and regulatory-ready. We handle the paperwork so your compliance and procurement teams can focus on formulation

Recommended Ingredient Pairings

Ingredient	Why It Pairs Well	Product Concept	Compatibility Note
Ceramide NP	Barrier-lipid support	Retinal night cream	Use appropriate lipid/emulsion architecture; validate active stability.
Niacinamide	Barrier, hydration and tone-care support	Night serum / cream	Validate pH, color and long-term stability.
Panthenol	Conditioning and comfort	Comfort-focused retinal treatment	Confirm preservation and full-formula stability.
Sodium Hyaluronate	Hydration and slip	Hydrating retinal serum	Aqueous vs lipophilic phase architecture matters.
Squalane	Emollient oil-phase option	Retinal facial oil / emulsion	Verify retinal solubility and oxidation stability.
Tocopherol	Oil-phase antioxidant support	Protected retinal oil phase	Does not replace assay-based stability testing.

Scientific Evidence Snapshot

Retinaldehyde has human topical evidence. A randomized double-blind study of 0.05% and 0.1% creams reported improved texture, hydration and TEWL, with melanin-index improvement only in the 0.1% group. [R3] A randomized split-face study of multilamellar-vesicle retinaldehyde reported improvements in wrinkle depth and aging-related biophysical parameters. [R4] Earlier human work also demonstrated biologic activity and topical tolerance. [R5]

Research & References

[R1] PubChem — Retinal (CID 638015)

[R2] European Commission CosIng — RETINAL, Ref 59127

[R3] Kwon HS et al. Retinaldehyde 0.1% and 0.05% creams in photoaged skin

[R4] Multilamellar-vesicle retinaldehyde randomized split-face study

[R5] Topical retinaldehyde on human skin: biologic effects and tolerance

[R6] 2024 topical-retinoid instability / carrier review

Frequently Asked Questions

What is Retinal?

Retinal, or retinaldehyde, is the aldehyde form of vitamin A and a direct precursor to retinoic acid.

Is Retinal the same as Retinol?

No. Retinol converts to retinal before retinal can convert to retinoic acid.

What use level is common?

Comparable pure-retinal supplier guidance commonly cites about 0.01–0.10% active basis; human finished-formula studies include 0.05% and 0.1%. [R3–R5,R8–R9]

Is Retinal 99% powder water soluble?

No conventional direct-aqueous dispersion should be assumed. Use a compatible lipid/solvent or delivery system and confirm the selected grade. [R8–R9]

Why is Retinal difficult to formulate?

Retinoids are sensitive to light, oxygen and temperature, so solubilization, processing and packaging strongly influence stability. [R6]

Does Retinal need encapsulation?

Not always. Encapsulation is one option when the formulation needs additional protection or controlled delivery.

Can it be paired with niacinamide, ceramides or hyaluronic acid?

Yes as formulation concepts, but phase and stability requirements must be validated in the actual formula.

What should I review before bulk purchase?

Confirm identity/isomer profile, assay method, residual solvents, stabilizer status, packaging, storage and required market documentation.

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Product: Retinal 99% Powder

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Retinal 99% Powder